Genome-wide DNA methylome profiling to differentiate monozygotic twins

Monozygotic (identical) twins share nearly identical genetic sequences, making it challenging to distinguish between them using conventional DNA profiling methods. Genome-wide DNA methylome profiling offers a powerful epigenetic approach to differentiate monozygotic twins by analyzing differences in DNA methylation patterns, which are influenced by environmental factors and individual life experiences. This method has significant implications in fields such as forensic science, personalized medicine, and developmental biology, providing deeper insight into gene regulation and individual epigenetic identity.

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